Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 10/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662045 | 0.87 | KIT (0.39) | SCN9A | |
| SCHEMBL31662607 | 0.79 | KIT (0.39) | — | |
| SCHEMBL31662072 | 0.79 | SCN9A (0.39) | SCN9ACD38CHEK2 | |
| SCHEMBL17888562 | 0.78 | PARP14 (0.35) | CHEK2PARP14PARP10 | |
| SCHEMBL31662035 | 0.78 | SCN9A (0.39) | SCN9ACD38CHEK2 | |
| SCHEMBL31662580 | 0.78 | PARP10 (0.46) | SCN9ACHEK2PARP14PARP10 | |
| SCHEMBL31661975 | 0.78 | CHEK2 (0.41) | SCN9ACD38CHEK2 | |
| SCHEMBL31662144 | 0.77 | PARP15 (0.51) | SCN9ACHEK2PARP10 | |
| SCHEMBL31662377 | 0.77 | SCN9A (0.43) | SCN9ACHEK2PARP10 | |
| SCHEMBL17899151 | 0.77 | ACACB (0.36) | SCN9AACACBPARP14PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |