Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662072 | 0.90 | SCN9A (0.39) | SCN9ACHEK2CD38HRH3 | |
| SCHEMBL31661975 | 0.90 | CHEK2 (0.41) | SCN9ACHEK2CD38HRH3 | |
| SCHEMBL31662592 | 0.88 | CHEK2 (0.48) | CHEK2 | |
| SCHEMBL31661893 | 0.87 | SCN9A (0.38) | SCN9ACD38HRH3 | |
| SCHEMBL31662085 | 0.87 | SCN9A (0.38) | SCN9ACD38HRH3 | |
| SCHEMBL31661960 | 0.84 | SCN1A (0.37) | SCN9ACHEK2RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL31662144 | 0.83 | PARP15 (0.51) | SCN9ACHEK2 | |
| SCHEMBL31662377 | 0.83 | SCN9A (0.43) | SCN9ACHEK2HRH3 | |
| SCHEMBL31662578 | 0.82 | CD38 (0.37) | SCN9ACD38SMN1; SMN2HRH3ALDH1A1 | |
| SCHEMBL31662417 | 0.82 | SCN9A (0.41) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |