Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662294 | 0.89 | HAO1 (0.39) | SCN9AKMT2A | |
| SCHEMBL31662519 | 0.87 | CA12 (0.41) | SCN9AALDH1A1KMT2A | |
| SCHEMBL31662377 | 0.84 | SCN9A (0.43) | PARP10SCN9AF2PRSS1PRSS2 | |
| SCHEMBL31662288 | 0.84 | AR (0.40) | SCN9AAR | |
| SCHEMBL31662417 | 0.83 | SCN9A (0.41) | PARP10SCN9AHPGDS | |
| SCHEMBL31662144 | 0.82 | PARP15 (0.51) | PARP10SCN9APARP15CHEK2 | |
| SCHEMBL31662222 | 0.82 | TBXAS1 (0.43) | SCN9AHPGDSKMT2A | |
| SCHEMBL31661931 | 0.79 | SCN9A (0.38) | PARP10SCN9ACCNCCDK8CHEK2 | |
| SCHEMBL31662290 | 0.76 | USP2 (0.39) | SCN9AALDH1A1KMT2A | |
| SCHEMBL31662483 | 0.76 | SYK (0.41) | PARP10SCN9AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |