Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 5/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662035 | 0.90 | SCN9A (0.39) | CHEK2SCN9ACD38HRH3 | |
| SCHEMBL31662228 | 0.90 | SCN9A (0.39) | CHEK2SCN9AKDM1ACD38JAK2 | |
| SCHEMBL31662072 | 0.89 | SCN9A (0.39) | CHEK2SCN9ACD38HRH3 | |
| SCHEMBL31661893 | 0.86 | SCN9A (0.38) | SCN9ACD38HRH3 | |
| SCHEMBL31662085 | 0.86 | SCN9A (0.38) | SCN9ACD38HRH3 | |
| SCHEMBL31661933 | 0.85 | SCN9A (0.39) | CHEK2SCN9AKDM1AREN | |
| SCHEMBL31662592 | 0.84 | CHEK2 (0.48) | CHEK2 | |
| SCHEMBL31661875 | 0.84 | SCN9A (0.40) | CHEK2SCN9AKDM1A | |
| SCHEMBL31662144 | 0.82 | PARP15 (0.51) | CHEK2SCN9A | |
| SCHEMBL31662377 | 0.82 | SCN9A (0.43) | CHEK2SCN9AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |