Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 3/20 | 0.34 |
| ▸ | RET | P07949 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MST1R | Q04912 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | CAMK4 | Q16566 | 1/20 | 0.34 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661995 | 0.90 | PDK2 (0.38) | PDK2CYP11B2HTR3AKDRSCN9A | |
| SCHEMBL31662183 | 0.90 | SCN9A (0.39) | PDK2DRD4SIGMAR1HTR3ARET | |
| SCHEMBL31662065 | 0.89 | PRKAB2 (0.39) | PDK2DRD4SIGMAR1HTR3ARET | |
| SCHEMBL31662023 | 0.86 | PDK2 (0.42) | PDK2KDM4EALDH1A1POLB | |
| SCHEMBL31662068 | 0.85 | CYP11B2 (0.36) | PDK2CYP11B2HTR3ASCN9AKDM4E | |
| SCHEMBL31662241 | 0.82 | PDK2 (0.38) | PDK2DRD4SIGMAR1HTR3ARET | |
| SCHEMBL31662140 | 0.82 | GAA (0.46) | DRD4SIGMAR1RETNTRK1KDM4E | |
| SCHEMBL31662469 | 0.82 | PRKAB2 (0.45) | PDK2DRD4SIGMAR1HTR3ARET | |
| SCHEMBL31662441 | 0.81 | SCN9A (0.37) | RETKDRPLK4NTRK1MET | |
| SCHEMBL31662208 | 0.81 | HPGD (0.42) | DRD4SIGMAR1NTRK1SCN9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |