Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.42 |
| ▸ | EGFR | P00533 | 7/20 | 0.41 |
| ▸ | ITK | Q08881 | 5/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662150 | 0.90 | CCNC (0.43) | PDK2EGFRITKCCNCCDK8 | |
| SCHEMBL31662065 | 0.88 | PRKAB2 (0.39) | PDK2EGFR | |
| SCHEMBL31662183 | 0.87 | SCN9A (0.39) | PDK2 | |
| SCHEMBL31661868 | 0.86 | PDK2 (0.38) | PDK2POLBALDH1A1KDM4E | |
| SCHEMBL31662208 | 0.83 | HPGD (0.42) | ALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL31661852 | 0.83 | PDK2 (0.38) | PDK2 | |
| SCHEMBL31662441 | 0.82 | SCN9A (0.37) | FFAR1 | |
| SCHEMBL31661880 | 0.81 | AXL (0.36) | SMN1; SMN2 | |
| SCHEMBL31661937 | 0.81 | PDE3B (0.39) | POLBALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL31662469 | 0.81 | PRKAB2 (0.45) | PDK2EGFRFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |