Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 11/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662270 | 0.90 | RET (0.36) | RETAXLGRM4IRAK4 | |
| SCHEMBL31662165 | 0.83 | IRAK4 (0.37) | RETIRAK4 | |
| SCHEMBL31661957 | 0.80 | IRAK4 (0.36) | IRAK4 | |
| SCHEMBL31661929 | 0.79 | IRAK4 (0.37) | RETIRAK4 | |
| SCHEMBL31662279 | 0.79 | IRAK4 (0.37) | RETIRAK4 | |
| SCHEMBL31662162 | 0.79 | IRAK4 (0.37) | RETIRAK4 | |
| SCHEMBL31662135 | 0.79 | IRAK4 (0.37) | RETIRAK4 | |
| SCHEMBL31662112 | 0.78 | ROCK2 (0.37) | RETIRAK4 | |
| SCHEMBL31661983 | 0.78 | CNR2 (0.32) | RETIRAK4 | |
| SCHEMBL31662113 | 0.77 | SCN9A (0.39) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |