Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 4/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662186 | 0.95 | CHEK2 (0.39) | PIK3CDCHEK2MAPK14NTRK1NTRK2 | |
| SCHEMBL31662540 | 0.87 | GPR119 (0.43) | CHEK2 | |
| SCHEMBL31661947 | 0.86 | SCN9A (0.36) | MAPK14SCN9AHRH3OPRM1OPRD1 | |
| SCHEMBL31662228 | 0.86 | SCN9A (0.39) | CHEK2SCN9AOPRM1OPRD1OPRK1 | |
| SCHEMBL31661933 | 0.85 | SCN9A (0.39) | CHEK2SCN9AOPRM1OPRD1OPRK1 | |
| SCHEMBL31662015 | 0.85 | SCN9A (0.36) | MAPK14SCN9AOPRM1OPRD1OPRK1 | |
| SCHEMBL31661963 | 0.85 | SCN9A (0.36) | MAPK14SCN9AOPRM1OPRD1OPRK1 | |
| SCHEMBL31662522 | 0.85 | SCN9A (0.36) | MAPK14SCN9AOPRM1OPRD1OPRK1 | |
| SCHEMBL31662120 | 0.84 | SCN9A (0.36) | PIK3CDNTRK1SCN9ANPC1RAB9A | |
| SCHEMBL31662603 | 0.81 | SCN9A (0.38) | SCN9AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |