Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662417 | 0.87 | SCN9A (0.41) | SCN9APARP10TBXAS1 | |
| SCHEMBL31662377 | 0.84 | SCN9A (0.43) | SCN9APARP10TBXAS1CHEK2 | |
| SCHEMBL31662222 | 0.83 | TBXAS1 (0.43) | SCN9ATBXAS1LMNA | |
| SCHEMBL31662189 | 0.82 | SCN9A (0.37) | SCN9ACCNCCDK8TSHRTSPO | |
| SCHEMBL31661942 | 0.80 | GAA (0.51) | SCN9ATSHRNPC1LMNAGAA | |
| SCHEMBL31662580 | 0.79 | PARP10 (0.46) | SCN9ACCNCCDK8PARP10CHEK2 | |
| SCHEMBL31662144 | 0.79 | PARP15 (0.51) | SCN9APARP10CHEK2 | |
| SCHEMBL31662175 | 0.78 | HRH3 (0.47) | LMNAMAPK1GAA | |
| SCHEMBL31662018 | 0.78 | SCN9A (0.39) | SCN9ACCNCCDK8TBXAS1CHEK2 | |
| SCHEMBL31662035 | 0.78 | SCN9A (0.39) | SCN9ACHEK2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |