Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662208 | 0.94 | HPGD (0.42) | PDE3BPDE3AHPGDMEN1ALDH1A1 | |
| SCHEMBL31662130 | 0.92 | PARP1 (0.40) | PDE3BPDE3AHPGDCYP2D6SMN1; SMN2 | |
| SCHEMBL31662140 | 0.92 | GAA (0.46) | PDE3BPDE3AHPGDCYP1A2CYP3A4 | |
| SCHEMBL31662211 | 0.91 | NTRK1 (0.40) | HPGDCYP2D6SMN1; SMN2NTRK1KCNH2 | |
| SCHEMBL31662714 | 0.90 | PDE3B (0.42) | PDE3BPDE3AROCK2SCN9AJAK2 | |
| SCHEMBL31662441 | 0.88 | SCN9A (0.37) | PDE3BPDE3ANTRK1ROCK2SCN9A | |
| SCHEMBL31662026 | 0.86 | SCN7A (0.37) | PDE3BPDE3ANTRK1SCN9AL3MBTL1 | |
| SCHEMBL31662000 | 0.83 | DRD4 (0.34) | NTRK1ROCK2SCN9ADRD4SIGMAR1 | |
| SCHEMBL31661959 | 0.82 | GAA (0.52) | PDE3BPDE3AHPGDALDH1A1CYP1A2 | |
| SCHEMBL31661966 | 0.81 | HPGD (0.39) | HPGDMEN1ALDH1A1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |