Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662211 | 0.91 | NTRK1 (0.40) | HPGDSMN1; SMN2CYP2D6NTRK1KCNH2 | |
| SCHEMBL31661959 | 0.89 | GAA (0.52) | HPGDSMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL31661856 | 0.85 | GAA (0.35) | HPGDSMN1; SMN2KMT2AGAASCN9A | |
| SCHEMBL31662291 | 0.84 | NTRK1 (0.38) | SMN1; SMN2ALDH1A1KDM1ANTRK1KCNH2 | |
| SCHEMBL31662493 | 0.83 | L3MBTL1 (0.41) | SCN9A | |
| SCHEMBL31661890 | 0.82 | NTRK1 (0.37) | KMT2AKDM1ANTRK1KCNH2NTRK2 | |
| SCHEMBL31662208 | 0.82 | HPGD (0.42) | HPGDSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL31661986 | 0.82 | CHEK2 (0.40) | SMN1; SMN2ALDH1A1NTRK1KCNH2NTRK2 | |
| SCHEMBL31662113 | 0.82 | SCN9A (0.39) | SCN9A | |
| SCHEMBL31662453 | 0.81 | MKNK1 (0.39) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |