Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | MST1R | Q04912 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | CAMK4 | Q16566 | 1/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662130 | 0.90 | PARP1 (0.40) | KCNH2PARP1SCN9APLK4NTRK1 | |
| SCHEMBL31662208 | 0.87 | HPGD (0.42) | KCNH2SCN9ANTRK1PDE2APDE3B | |
| SCHEMBL31661937 | 0.86 | PDE3B (0.39) | SCN7AKCNH2L3MBTL1SCN9ANTRK1 | |
| SCHEMBL31662140 | 0.85 | GAA (0.46) | NTRK1RETPDE2APDE3BPDE3A | |
| SCHEMBL31662211 | 0.84 | NTRK1 (0.40) | KCNH2NTRK1 | |
| SCHEMBL31662183 | 0.84 | SCN9A (0.39) | SCN9APLK4NTRK1RETMET | |
| SCHEMBL31662441 | 0.83 | SCN9A (0.37) | L3MBTL1SCN9APLK4NTRK1RET | |
| SCHEMBL31662714 | 0.82 | PDE3B (0.42) | PARP1SCN9APDE3BPDE3A | |
| SCHEMBL31662000 | 0.79 | DRD4 (0.34) | SCN9APLK4NTRK1RETMET | |
| SCHEMBL31662023 | 0.78 | PDK2 (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |