Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662208 | 0.92 | HPGD (0.42) | NTRK1KCNH2NTRK2DRD4SIGMAR1 | |
| SCHEMBL31661937 | 0.91 | PDE3B (0.39) | NTRK1KCNH2CYP2D6DRD4SIGMAR1 | |
| SCHEMBL31661966 | 0.91 | HPGD (0.39) | NTRK1KCNH2NTRK2NTRK3CYP2D6 | |
| SCHEMBL31662140 | 0.89 | GAA (0.46) | NTRK1DRD4SIGMAR1HPGDSMN1; SMN2 | |
| SCHEMBL31662130 | 0.89 | PARP1 (0.40) | NTRK1KCNH2NTRK2CYP2D6HPGD | |
| SCHEMBL31662714 | 0.87 | PDE3B (0.42) | GPR119 | |
| SCHEMBL31662441 | 0.85 | SCN9A (0.37) | NTRK1PARP10 | |
| SCHEMBL31662120 | 0.85 | SCN9A (0.36) | NTRK1CYP2D6PIK3CDEGFRERBB2 | |
| SCHEMBL31662026 | 0.84 | SCN7A (0.37) | NTRK1KCNH2 | |
| SCHEMBL31662000 | 0.83 | DRD4 (0.34) | NTRK1DRD4SIGMAR1PARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |