Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662468 | 0.84 | HTR3A (0.33) | HRH3SCN9AHTR3A | |
| SCHEMBL31662003 | 0.83 | HRH3 (0.38) | HRH3SCN9AHTR3A | |
| SCHEMBL31661971 | 0.83 | SCN9A (0.36) | HRH3SCN9AOPRM1OPRD1OPRK1 | |
| SCHEMBL31661921 | 0.81 | TLR7 (0.42) | HRH3HTR3A | |
| SCHEMBL31662240 | 0.81 | SCN9A (0.35) | HRH3SCN9AOPRM1OPRD1OPRK1 | |
| SCHEMBL31662603 | 0.81 | SCN9A (0.38) | SCN9AOPRM1OPRD1OPRK1 | |
| SCHEMBL31662138 | 0.80 | DRD4 (0.43) | HRH3 | |
| SCHEMBL31661963 | 0.80 | SCN9A (0.36) | SCN9AOPRM1OPRD1OPRK1 | |
| SCHEMBL31662522 | 0.80 | SCN9A (0.36) | SCN9AOPRM1OPRD1OPRK1 | |
| SCHEMBL31661947 | 0.80 | SCN9A (0.36) | HRH3SCN9AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |