Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 2/20 | 0.32 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | HRH2 | P25021 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661956 | 0.84 | HRH3 (0.35) | HTR3ASCN9AHRH3 | |
| SCHEMBL31662235 | 0.78 | CD38 (0.39) | RENBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL31661940 | 0.78 | HTR3A (0.32) | HTR3A | |
| SCHEMBL31662377 | 0.71 | SCN9A (0.43) | SCN9AHRH3 | |
| SCHEMBL31662175 | 0.70 | HRH3 (0.47) | HRH3 | |
| SCHEMBL31662085 | 0.70 | SCN9A (0.38) | SCN9AHRH3 | |
| SCHEMBL31662527 | 0.70 | MAPT (0.41) | SCN9A | |
| SCHEMBL31662072 | 0.70 | SCN9A (0.39) | SCN9AHRH3 | |
| SCHEMBL31662144 | 0.69 | PARP15 (0.51) | SCN9A | |
| SCHEMBL31662222 | 0.68 | TBXAS1 (0.43) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |