Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662176 | 0.94 | SCN9A (0.39) | SCN9ANPC1RAB9APDE4DCHEK2 | |
| SCHEMBL31662160 | 0.90 | SCN9A (0.36) | SCN9APDE4DOPRK1OPRM1OPRD1 | |
| SCHEMBL31662072 | 0.90 | SCN9A (0.39) | SCN9APDE4DCHEK2CD38 | |
| SCHEMBL31661947 | 0.85 | SCN9A (0.36) | SCN9APDE4DOPRK1OPRM1OPRD1 | |
| SCHEMBL31662085 | 0.85 | SCN9A (0.38) | SCN9AKCNH2PDE4DCD38 | |
| SCHEMBL31661893 | 0.85 | SCN9A (0.38) | SCN9AKCNH2PDE4DCD38 | |
| SCHEMBL31662578 | 0.82 | CD38 (0.37) | SCN9APDE4DCD38 | |
| SCHEMBL31662235 | 0.82 | CD38 (0.39) | SCN9AKCNH2PDE4DCD38 | |
| SCHEMBL31662620 | 0.81 | CD38 (0.40) | RAB9APDE4DCD38LRRK2 | |
| SCHEMBL31662035 | 0.81 | SCN9A (0.39) | SCN9ANPC1RAB9ACHEK2CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |