SCHEMBL31662047

SCHEMBL31662047

CCC(=O)NC(C)c1ccc(F)c(O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 1/20 0.48
ADRA2A P08913 1/20 0.48
ADRB3 P13945 1/20 0.48
ADRA2B P18089 1/20 0.48
ADRA2C P18825 1/20 0.48
HTT P42858 2/20 0.47
ALDH1A1 P00352 4/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ACACB O00763 1/20 0.44
ACACA Q13085 1/20 0.44
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
CRHBP P24387 1/20 0.43
MAPK1 P28482 1/20 0.43
CRHR2 Q13324 1/20 0.43
CNR1 P21554 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22723318 0.83 ADRB1 (0.47) ADRB1ADRA2AADRB3ADRA2BADRA2C
SCHEMBL20188222 0.83 ADRB1 (0.47) ADRB1ADRA2AADRB3ADRA2BADRA2C
SCHEMBL31662030 0.81 CNR1 (0.48) SMN1; SMN2ACACBACACAHPGDCNR1
SCHEMBL19658757 0.79 HTT (0.71) HTTALDH1A1LMNAKDM4EMEN1
SCHEMBL14535437 0.79 HTT (0.71) HTTALDH1A1LMNAKDM4EMEN1
SCHEMBL31661855 0.78 ACACB (0.46) ADRB1ADRA2AADRB3ADRA2BADRA2C
SCHEMBL31036982 0.77 GPR139 (0.56) HTTALDH1A1LMNAKDM4EMEN1
SCHEMBL8445815 0.76 GPR139 (0.55) HTTALDH1A1LMNASMN1; SMN2MEN1
SCHEMBL31036979 0.76 HTT (0.49) HTTALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL20201946 0.75 TRPA1 (0.43) ADRB1ADRA2AADRB3ADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149629-A1 NOVEL CARBOXAMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-17 WO disclosed