Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGDS | O60760 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662059 | 0.89 | PDE4D (0.35) | CD38PDE4DNAMPT | |
| SCHEMBL31662620 | 0.82 | CD38 (0.40) | CD38MAPTHPGDSL3MBTL1TDP1 | |
| SCHEMBL17888595 | 0.78 | MAPT (0.44) | MAPTL3MBTL1TDP1PDE4DRAB9A | |
| SCHEMBL31662343 | 0.77 | DGAT1 (0.34) | MAPTHPGDSPDE4DRAB9AKDM4E | |
| SCHEMBL31662148 | 0.76 | BTK (0.37) | L3MBTL1RAB9AMEN1NPC1KMT2A | |
| SCHEMBL31662277 | 0.74 | MAPT (0.38) | MAPTHPGDSL3MBTL1TDP1RAB9A | |
| SCHEMBL31662261 | 0.74 | MAPT (0.34) | MAPTHPGDSL3MBTL1TDP1RAB9A | |
| SCHEMBL31662303 | 0.74 | CHEK1 (0.39) | MAPT | |
| SCHEMBL31662302 | 0.74 | CHEK1 (0.39) | MAPT | |
| SCHEMBL31662770 | 0.74 | CD38 (0.36) | CD38MAPTPDE4BLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |