Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662421 | 0.86 | MCL1 (0.44) | SYKNOTUMMEN1KMT2AMCL1 | |
| SCHEMBL31662505 | 0.84 | CA12 (0.48) | ROCK2 | |
| SCHEMBL31662453 | 0.82 | MKNK1 (0.39) | SYKROCK2NOTUMMCL1HAO1 | |
| SCHEMBL31662483 | 0.82 | SYK (0.41) | SYKNOTUMHAO1 | |
| SCHEMBL31662511 | 0.81 | SYK (0.38) | SYKNOTUMMCL1HAO1 | |
| SCHEMBL31662092 | 0.81 | SYK (0.37) | SYKROCK2NOTUMMCL1HAO1 | |
| SCHEMBL31662493 | 0.81 | L3MBTL1 (0.41) | SYKNOTUMMCL1HAO1 | |
| SCHEMBL31662602 | 0.80 | PARP10 (0.46) | SYKMEN1NPC1RAB9AKMT2A | |
| SCHEMBL31662285 | 0.79 | FKBP1A (0.50) | NPC1RAB9A | |
| SCHEMBL31662521 | 0.78 | SCN9A (0.41) | SYKNOTUMHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |