Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 4/20 | 0.33 |
| ▸ | GSK3B | P49841 | 4/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.33 |
| ▸ | KRAS | P01116 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661940 | 0.93 | HTR3A (0.32) | HTR3A | |
| SCHEMBL31662373 | 0.89 | KCNH2 (0.34) | KCNH2MCHR1ESR1ESR2WNT1 | |
| SCHEMBL31661927 | 0.86 | HRH3 (0.33) | KCNH2HTR3A | |
| SCHEMBL31661962 | 0.79 | TTK (0.35) | — | |
| SCHEMBL31662425 | 0.74 | HRH3 (0.33) | KCNH2HTR3A | |
| SCHEMBL31662158 | 0.72 | NPBWR1 (0.34) | MCHR1GSK3B | |
| SCHEMBL31662111 | 0.71 | MCHR2 (0.33) | MCHR1 | |
| SCHEMBL31662146 | 0.71 | MCHR2 (0.35) | MCHR1 | |
| SCHEMBL31662273 | 0.70 | MCHR2 (0.34) | MCHR1 | |
| SCHEMBL31662154 | 0.70 | TUBB4A (0.34) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |