Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662425 | 0.88 | HRH3 (0.33) | HRH3HTR3AMAOBKCNH2KDM4E | |
| SCHEMBL31662212 | 0.86 | KCNH2 (0.34) | HTR3AKCNH2 | |
| SCHEMBL31661940 | 0.83 | HTR3A (0.32) | HTR3A | |
| SCHEMBL31661962 | 0.82 | TTK (0.35) | TTK | |
| SCHEMBL31662158 | 0.77 | NPBWR1 (0.34) | TTKGPR119 | |
| SCHEMBL31662373 | 0.74 | KCNH2 (0.34) | HTR3AKCNH2 | |
| SCHEMBL31662146 | 0.74 | MCHR2 (0.35) | HRH3TTKGPR119 | |
| SCHEMBL31662273 | 0.73 | MCHR2 (0.34) | GPR119 | |
| SCHEMBL31662154 | 0.73 | TUBB4A (0.34) | TTKGPR119 | |
| SCHEMBL31661923 | 0.72 | TTK (0.38) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |