Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 16/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661954 | 0.93 | TTK (0.32) | TTKLRRK2CD38HTR6 | |
| SCHEMBL31661962 | 0.91 | TTK (0.35) | TTKLRRK2CD38HTR6 | |
| SCHEMBL31661978 | 0.90 | TTK (0.35) | TTKGSK3BDYRK1ACCNA2CDK2 | |
| SCHEMBL31662202 | 0.87 | GSK3B (0.36) | TTKGSK3BDYRK1ALRRK2CD38 | |
| SCHEMBL31661988 | 0.84 | LRRK2 (0.36) | GSK3BDYRK1ALRRK2CD38HTR6 | |
| SCHEMBL31662230 | 0.82 | CD38 (0.34) | LRRK2CD38HTR6 | |
| SCHEMBL31662457 | 0.82 | CD38 (0.34) | LRRK2CD38HTR6 | |
| SCHEMBL31662171 | 0.81 | TTK (0.36) | TTKGSK3BDYRK1ACCNA2CDK2 | |
| SCHEMBL31661898 | 0.79 | TTK (0.34) | TTKGSK3BDYRK1ACCNA2CDK2 | |
| SCHEMBL31662578 | 0.79 | CD38 (0.37) | CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |