Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | AOC2 | O75106 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662323 | 0.88 | ADRB2 (0.35) | MAPTADRB2ADRB1OPRK1KAT2B | |
| SCHEMBL31662586 | 0.88 | ADRB2 (0.36) | MAPTADRB2ADRB1OPRK1KAT2B | |
| SCHEMBL31662302 | 0.85 | CHEK1 (0.39) | MAPTRORC | |
| SCHEMBL31662303 | 0.85 | CHEK1 (0.39) | MAPTRORC | |
| SCHEMBL31662063 | 0.85 | CA1 (0.33) | ADRB2ADRB1 | |
| SCHEMBL31662770 | 0.79 | CD38 (0.36) | MAPTOPRK1RORC | |
| SCHEMBL31662538 | 0.79 | OPRK1 (0.33) | MAPTADRB2ADRB1OPRK1KAT2B | |
| SCHEMBL31662544 | 0.79 | KAT2B (0.35) | MAPTADRB2ADRB1OPRK1KAT2B | |
| SCHEMBL31662611 | 0.77 | PDE4B (0.36) | MAPTOPRK1RORC | |
| SCHEMBL17888595 | 0.76 | MAPT (0.44) | MAPTRAB9AHPGDNPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |