Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662331 | 0.91 | DHODH (0.36) | KAT2BGSK3BCD38BAZ2B | |
| SCHEMBL31661952 | 0.90 | RET (0.34) | KAT2BGSK3BCD38BAZ2BP2RX3 | |
| SCHEMBL31662538 | 0.86 | OPRK1 (0.33) | KAT2BCD38MRGPRX4OPRK1ADRB2 | |
| SCHEMBL31662261 | 0.79 | MAPT (0.34) | KAT2BBAZ2BTDP1L3MBTL1OPRK1 | |
| SCHEMBL31662303 | 0.79 | CHEK1 (0.39) | P2RX3MAPT | |
| SCHEMBL31662302 | 0.79 | CHEK1 (0.39) | P2RX3MAPT | |
| SCHEMBL31662770 | 0.78 | CD38 (0.36) | CD38OPRK1P2RX3MAPT | |
| SCHEMBL31662323 | 0.77 | ADRB2 (0.35) | KAT2BOPRK1ADRB2ADRB1P2RX3 | |
| SCHEMBL31662611 | 0.76 | PDE4B (0.36) | OPRK1MAPTMEN1KMT2A | |
| SCHEMBL31662332 | 0.76 | MIF (0.34) | KAT2BKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |