Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27459219 | 0.84 | MAOB (0.61) | APPMAOBMAOASMPD1FFAR1 | |
| SCHEMBL1532839 | 0.83 | LMNA (0.59) | MAOBMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27437785 | 0.83 | MAOB (0.55) | APPMAOBMAOANPC1RAB9A | |
| SCHEMBL27433328 | 0.81 | ESR2 (0.57) | MAOBMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3613914 | 0.81 | ALDH1A1 (0.53) | APPMAOBNPC1RAB9APOLB | |
| SCHEMBL754809 | 0.80 | ALDH1A1 (0.55) | NPC1RAB9ASMN1; SMN2TDP1ALOX15 | |
| SCHEMBL27458400 | 0.80 | MAOB (0.55) | MAOBMAOA | |
| SCHEMBL27435079 | 0.80 | GCGR (0.49) | MAOBMAOA | |
| SCHEMBL9650323 | 0.80 | NR5A1 (0.56) | MAOBMAOANPC1RAB9A | |
| SCHEMBL8409305 | 0.79 | CALM1 (0.50) | APPMAOBNPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |