SCHEMBL754809

SCHEMBL754809

COc1ccc(O)c(Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
KDM4E B2RXH2 1/20 0.55
GAA P10253 1/20 0.55
MAPT P10636 1/20 0.55
THRB P10828 1/20 0.55
RECQL P46063 1/20 0.55
BLM P54132 1/20 0.55
MCL1 Q07820 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
ERN1 O75460 1/20 0.52
TSHR P16473 1/20 0.50
HSD17B10 Q99714 1/20 0.50
NPC1 O15118 2/20 0.48
RAB9A P51151 1/20 0.48
CYP3A4 P08684 2/20 0.47
TRIM24 O15164 1/20 0.47
TYR P14679 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5981416 0.83 ESR2 (0.64) CYP3A4HSP90AA1HSP90AB1
SCHEMBL1000565 0.82 NPC1 (0.53) ALDH1A1MEN1KMT2AKDM4EGAA
SCHEMBL258619 0.81 HSP90AA1 (0.57) ALDH1A1MEN1KMT2ATHRBTSHR
SCHEMBL31662278 0.80 APP (0.51) SMN1; SMN2TDP1NPC1RAB9AALOX15
SCHEMBL5671970 0.79 APP (0.59) ALDH1A1MEN1KMT2AKDM4EGAA
SCHEMBL67498 0.78 ALDH1A1 (0.61) ALDH1A1MEN1KMT2AKDM4EGAA
SCHEMBL1145316 0.78 SLC6A4 (0.54) KDM4ECA1CA2HSP90AA1HSP90AB1
SCHEMBL29950410 0.78 ALDH1A1 (0.61) ALDH1A1MEN1KMT2AKDM4EGAA
SCHEMBL29768449 0.78 SLC6A4 (0.54) KDM4ECA1CA2HSP90AA1HSP90AB1
SCHEMBL1958623 0.78 TSHR (0.42) ALDH1A1KDM4EMAPTMCL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120009363-A Disposable paper-based electrode for sensitively detecting 2-chloro-4-methoxyphenol and preparation method and application thereof 信阳师范大学 2025-05-16 CN claimed
US-10035033-B2 Fire extinguishing composition comprising alcohol phenol compound and derivative thereof XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) 2018-07-31 US claimed
EP-3095486-A2 FIRE EXTINGUISHING COMPOSITION COMPRISING ALCOHOL PHENOL COMPOUND AND DERIVATIVE THEREOF Xi'an J&R Fire Fighting Equipment Co., Ltd. (CN) 2016-11-23 EP claimed
EP-3095487-A1 FIRE EXTINGUISHING COMPOSITION COMPRISING ALDOKETONES COMPOUND Xi'an J&R Fire Fighting Equipment Co., Ltd. (CN) 2016-11-23 EP claimed
US-20160332014-A1 Fire Extinguishing Composition Comprising Alcohol Phenol Compound and Derivative Thereof NANO FIRE, LLC 2016-11-17 US claimed
WO-2016029146-A1 SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE UNIVERSITY OF WASHINGTON (US) 2016-02-25 WO claimed
CN-103063764-A Detection method for residual quantity of multiple preservatives in cosmetics LIN WEIXUAN 2013-04-24 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
US-5149858-A Reacting with chlorine gas in presence of organic cation catalysts RHONE-POULENC CHIMIE (FR) 1992-09-22 US claimed
EP-0216714-B1 PROCESS FOR THE SELECTIVE CHLORINATION OF PHENOLIC COMPOUNDS RHONE-POULENC CHIMIE (FR) 1992-05-13 EP claimed
EP-0299891-B1 PROCESS FOR THE SELECTIVE CHLORINATION OF PHENOLIC COMPOUNDS RHONE-POULENC CHIMIE (FR) 1991-12-11 EP claimed
US-4876396-A AT ORTHO POSITION TO HYDROXYL; AMINE CATALYSTS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1989-10-24 US claimed
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US disclosed
US-20260001861-A1 PYRIDINE CARBOXAMIDE COMPOUNDS FOR INHIBITING NAV1.8 LIEBER INST INC (US) 2026-01-01 US disclosed
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP disclosed
US-4182727-A 4-[6-(4-Cyanophenoxy)hexyl]-3,5-heptanedione STERLING DRUG INC. (US) 1980-01-08 US disclosed
US-4171376-A Aryloxyalkyl keto-esters STERLING DRUG INC. (US) 1979-10-16 US disclosed
US-4153719-A Aromatic diketones STERLING DRUG INC. (US) 1979-05-08 US disclosed
US-3904695-A Preparation of phloroglucinol and its mono-ethers ANDENO NV 1975-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof CBR1, CBR3, HCCS ALDH1A1 2035/4885MEN1 3874/4885KMT2A 3264/4885
US-20260001861-A1 PYRIDINE CARBOXAMIDE COMPOUNDS FOR INHIBITING NAV1.8 SCN8A, SCN1A, SCN1B ALDH1A1 1730/4885MEN1 3364/4885KMT2A 2792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.