Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | HPGDS | O60760 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662620 | 0.86 | CD38 (0.40) | MAPTHPGDSPDE4DALDH1A1TSHR | |
| SCHEMBL31662574 | 0.83 | DGAT1 (0.37) | DGAT1MAPTALDH1A1TSHRKMT2A | |
| SCHEMBL31662372 | 0.79 | IRAK4 (0.33) | DGAT1 | |
| SCHEMBL31662578 | 0.78 | CD38 (0.37) | HPGDSPDE4DALDH1A1KMT2AMAPK14 | |
| SCHEMBL31662235 | 0.78 | CD38 (0.39) | HPGDSPDE4DMAPK14 | |
| SCHEMBL31662467 | 0.78 | CD38 (0.37) | HPGDSPDE4DMAPK14 | |
| SCHEMBL31662072 | 0.77 | SCN9A (0.39) | PDE4DMAPK14 | |
| SCHEMBL31662413 | 0.77 | CD38 (0.39) | MAPTHPGDSPDE4DALDH1A1KMT2A | |
| SCHEMBL31662611 | 0.75 | PDE4B (0.36) | MAPTKMT2ANPSR1MEN1 | |
| SCHEMBL31662006 | 0.75 | GCK (0.43) | ALDH1A1KMT2ASMN1; SMN2HPGDLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |