Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 2/20 | 0.30 |
| ▸ | JAK3 | P52333 | 2/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662165 | 0.86 | IRAK4 (0.37) | IRAK4TBK1JAK1JAK3JAK2 | |
| SCHEMBL31661957 | 0.84 | IRAK4 (0.36) | IRAK4TBK1PDE4BJAK1JAK3 | |
| SCHEMBL31662142 | 0.83 | IRAK4 (0.39) | IRAK4TBK1PDE4B | |
| SCHEMBL31662129 | 0.83 | MAPK1 (0.38) | IRAK4TBK1JAK1JAK3 | |
| SCHEMBL31661929 | 0.82 | IRAK4 (0.37) | IRAK4TBK1JAK1JAK3JAK2 | |
| SCHEMBL31662016 | 0.82 | SYK (0.36) | IRAK4TBK1JAK1JAK3JAK2 | |
| SCHEMBL31662162 | 0.81 | IRAK4 (0.37) | IRAK4TBK1JAK1JAK3JAK2 | |
| SCHEMBL31662475 | 0.81 | GCK (0.34) | PDE4B | |
| SCHEMBL31662135 | 0.81 | IRAK4 (0.37) | IRAK4TBK1JAK1JAK3JAK2 | |
| SCHEMBL31662279 | 0.81 | IRAK4 (0.37) | IRAK4TBK1JAK1JAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |