Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GCK | P35557 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 2/20 | 0.32 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662235 | 0.87 | CD38 (0.39) | CD38GCKMAPK14HPGDSREN | |
| SCHEMBL31662620 | 0.84 | CD38 (0.40) | CD38RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL31662578 | 0.84 | CD38 (0.37) | CD38GCKKDM4EALDH1A1MEN1 | |
| SCHEMBL31662072 | 0.83 | SCN9A (0.39) | CD38MAPK14SCN9A | |
| SCHEMBL31662006 | 0.80 | GCK (0.43) | GCKALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31662085 | 0.79 | SCN9A (0.38) | CD38GCKHPGDSSCN9A | |
| SCHEMBL31661893 | 0.79 | SCN9A (0.38) | CD38GCKHPGDSSCN9A | |
| SCHEMBL31662508 | 0.78 | CD38 (0.37) | CD38GCKMAPK14BMPR1BBMPR1A | |
| SCHEMBL31662457 | 0.77 | CD38 (0.34) | CD38ALDH1A1MAPK14SMN1; SMN2CYP1A2 | |
| SCHEMBL31662230 | 0.77 | CD38 (0.34) | CD38ALDH1A1LMNAMAPK14CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |