SCHEMBL31662367

SCHEMBL31662367

Cn1ncc2nc(C#N)c(Br)cc21

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.31
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25173194 0.78 EGFR (0.32)
SCHEMBL30971302 0.77 CYP11B2 (0.32) KDM1ACYP11B2
SCHEMBL15410150 0.74 PIK3CB (0.33)
SCHEMBL31602718 0.72 KDM1A (0.36) KDM1A
SCHEMBL31752152 0.71 ALDH1A1 (0.40)
SCHEMBL31586750 0.69 TDP1 (0.43)
SCHEMBL31753089 0.68 HTT (0.34)
SCHEMBL31752124 0.68 HPGDS (0.41) KDM1ACYP11B2
SCHEMBL23529927 0.68 NQO1 (0.40) KDM1ACYP11B2
SCHEMBL30791989 0.68 NQO1 (0.40) KDM1ACYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149545-A1 HETEROARYLPHENYL ETHER DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2025-07-17 WO disclosed