Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662611 | 0.92 | PDE4B (0.36) | GCKPDE4BMAPK1MAT2ANOTUM | |
| SCHEMBL31662428 | 0.90 | DHODH (0.37) | DHODHMIFMAPK1KDM4E | |
| SCHEMBL31661945 | 0.83 | LRRK2 (0.36) | MAPK1KDM4E | |
| SCHEMBL31662165 | 0.82 | IRAK4 (0.37) | — | |
| SCHEMBL31662770 | 0.82 | CD38 (0.36) | PDE4BMAPK1 | |
| SCHEMBL31662372 | 0.81 | IRAK4 (0.33) | PDE4B | |
| SCHEMBL31661957 | 0.80 | IRAK4 (0.36) | PDE4BMAPK1 | |
| SCHEMBL31662142 | 0.80 | IRAK4 (0.39) | GCKPDE4BMAPK1 | |
| SCHEMBL31662412 | 0.79 | DRD4 (0.35) | DHODHMIFMAPK1 | |
| SCHEMBL31662129 | 0.79 | MAPK1 (0.38) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |