Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | PIR | O00625 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10537261 | 0.90 | AR (0.47) | ARCA12CA1CA9PPARD | |
| SCHEMBL31042804 | 0.84 | CA12 (0.44) | CA12CA1CA9KEAP1NFE2L2 | |
| SCHEMBL6919116 | 0.81 | AR (0.47) | ARCA12CA1CA9KEAP1 | |
| SCHEMBL7371569 | 0.78 | AR (0.56) | ARFFAR1CA12CA1CA9 | |
| SCHEMBL1109820 | 0.77 | DRD2 (0.50) | ARCA12CA1CA9 | |
| SCHEMBL11259445 | 0.77 | AR (0.48) | ARCA12CA1CA9KEAP1 | |
| SCHEMBL13020433 | 0.77 | CA12 (0.58) | CA12CA1CA9 | |
| SCHEMBL2246161 | 0.76 | ALDH1A1 (0.49) | ARCA12CA1CA9PIR | |
| SCHEMBL23213491 | 0.76 | LMNA (0.42) | ARMRGPRX4KEAP1NFE2L2PIR | |
| SCHEMBL31748240 | 0.76 | CA12 (0.49) | ARCA12CA1CA9PIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |