Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662349 | 0.86 | GPR119 (0.36) | GPR119MCHR2MCHR1SCN9ASYK | |
| SCHEMBL31662483 | 0.81 | SYK (0.41) | PARP10SCN9ASYKIRAK4PDE1C | |
| SCHEMBL31661984 | 0.80 | IKBKB (0.42) | MCHR2MCHR1HTR1APRMT5 | |
| SCHEMBL31662129 | 0.80 | MAPK1 (0.38) | GPR119JAK1JAK3SYKIRAK4 | |
| SCHEMBL31661918 | 0.78 | GPR119 (0.34) | GPR119PRMT5 | |
| SCHEMBL31662194 | 0.71 | SCN9A (0.43) | SCN9APDE1C | |
| SCHEMBL31662113 | 0.71 | SCN9A (0.39) | SCN9ASYKIRAK4 | |
| SCHEMBL31662421 | 0.69 | MCL1 (0.44) | SCN9ASYKPRMT5 | |
| SCHEMBL31662453 | 0.69 | MKNK1 (0.39) | SCN9ASYK | |
| SCHEMBL22843175 | 0.66 | RXRA (0.48) | PARP10KCNH2SYKIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |