Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.41 |
| ▸ | DRD3 | P35462 | 7/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662406 | 0.87 | SCN9A (0.43) | DRD2RAB9AHDAC1DRD3SCN9A | |
| SCHEMBL18361665 | 0.80 | CA1 (0.48) | DRD2RAB9A | |
| SCHEMBL31662444 | 0.79 | RAB9A (0.47) | DRD2RAB9AHDAC1DRD3KCNH2 | |
| SCHEMBL3135147 | 0.74 | HDAC1 (0.67) | DRD2RAB9AHDAC1DRD3CYP2D6 | |
| SCHEMBL10498451 | 0.74 | KDM4E (0.49) | DRD2RAB9AHDAC1DRD3 | |
| SCHEMBL31662551 | 0.73 | DRD2 (0.48) | DRD2RAB9AHDAC1DRD3SCN9A | |
| SCHEMBL31662436 | 0.72 | F10 (0.43) | RAB9ASCN9AESR1ESR2MEN1 | |
| SCHEMBL3712107 | 0.72 | S1PR1 (0.48) | DRD2RAB9AHDAC1DRD3KCNH2 | |
| SCHEMBL8558181 | 0.71 | S1PR1 (0.50) | DRD2RAB9AHDAC1DRD3KCNH2 | |
| SCHEMBL19244580 | 0.71 | ALDH1A1 (0.52) | RAB9AHDAC1ESR1ESR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |