Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646449 | 0.76 | GABRA1 (0.47) | AURKAGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7219030 | 0.76 | AURKA (0.68) | AURKAGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL3433644 | 0.75 | IMPDH2 (0.59) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30678031 | 0.75 | IMPDH2 (0.59) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL13596793 | 0.73 | IMPDH2 (0.58) | AURKAGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL647434 | 0.73 | AXL (0.47) | AURKAGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL22433744 | 0.73 | ERBB2 (0.50) | AURKAGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5914563 | 0.73 | TDP1 (0.59) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL644972 | 0.73 | TYMS (0.53) | AURKAGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30198203 | 0.73 | PDK2 (0.57) | AURKAGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151874-A1 | INDOLE ALKALOID ANTIPLASMODIAL AGENTS AND PREPARATION THEREOF | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2025-07-17 | — | — | WO | disclosed |