Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.38 |
| ▸ | PDE4A | P27815 | 4/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.35 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662943 | 0.88 | PDE4D (0.38) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL31662882 | 0.84 | DRD1 (0.40) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL31663072 | 0.80 | PDE4D (0.41) | PDE4D | |
| SCHEMBL31663278 | 0.73 | GRIN2B (0.37) | — | |
| SCHEMBL31662955 | 0.73 | SMN1; SMN2 (0.38) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL28060611 | 0.73 | DRD1 (0.51) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL31663302 | 0.73 | PHGDH (0.34) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL31663184 | 0.72 | PTGES (0.38) | PDE4DMAP3K12 | |
| SCHEMBL17279865 | 0.72 | TACR3 (0.46) | TACR3TP53MDM2ALDH1A1LMNA | |
| SCHEMBL31663238 | 0.72 | CHRNB2 (0.34) | PDE4DPDE4APDE4BPDE4CTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |