Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.37 |
| ▸ | ASIC1 | P78348 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663072 | 0.95 | PDE4D (0.41) | DRD1PDE4DASIC1POLBNPSR1 | |
| SCHEMBL31663302 | 0.87 | PHGDH (0.34) | DRD1PDE4DASIC1PDE4APDE4B | |
| SCHEMBL31662943 | 0.86 | PDE4D (0.38) | DRD1PDE4DPOLBPDE4APDE4B | |
| SCHEMBL31662999 | 0.85 | GRIN2B (0.35) | DRD1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL31662858 | 0.84 | TACR3 (0.38) | PDE4DPDE4APDE4BPDE4CLMNA | |
| SCHEMBL31663238 | 0.84 | CHRNB2 (0.34) | DRD1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL31663086 | 0.83 | GRIN2B (0.35) | PDE4D | |
| SCHEMBL31662955 | 0.79 | SMN1; SMN2 (0.38) | DRD1PDE4DPOLBPDE4APDE4B | |
| SCHEMBL28060611 | 0.79 | DRD1 (0.51) | DRD1POLBLMNAHPGDSMN1; SMN2 | |
| SCHEMBL31662933 | 0.76 | HPGDS (0.45) | DRD1PDE4DPOLBPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |