Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 13/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662882 | 0.95 | DRD1 (0.40) | PDE4DDRD1ASIC1NPSR1STIM1 | |
| SCHEMBL31663302 | 0.85 | PHGDH (0.34) | PDE4DDRD1ASIC1 | |
| SCHEMBL31662999 | 0.83 | GRIN2B (0.35) | PDE4DDRD1PDE5A | |
| SCHEMBL31663238 | 0.82 | CHRNB2 (0.34) | PDE4DDRD1 | |
| SCHEMBL31662943 | 0.81 | PDE4D (0.38) | PDE4DDRD1POLB | |
| SCHEMBL31663086 | 0.81 | GRIN2B (0.35) | PDE4D | |
| SCHEMBL31662858 | 0.80 | TACR3 (0.38) | PDE4D | |
| SCHEMBL31662933 | 0.79 | HPGDS (0.45) | PDE4DDRD1NPSR1POLB | |
| SCHEMBL28060611 | 0.79 | DRD1 (0.51) | DRD1POLB | |
| SCHEMBL31662955 | 0.76 | SMN1; SMN2 (0.38) | PDE4DDRD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |