SCHEMBL31662886

SCHEMBL31662886

NCc1ccc(N2CCNC(=O)C2)nc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 1/20 0.45
PRMT5 O14744 2/20 0.41
PIM1 P11309 3/20 0.40
PIM3 Q86V86 1/20 0.40
PIM2 Q9P1W9 1/20 0.40
ALOX5AP P20292 1/20 0.40
CCNT1 O60563 1/20 0.39
CDK4 P11802 1/20 0.39
CCND1 P24385 1/20 0.39
CCND3 P30281 1/20 0.39
CDK9 P50750 1/20 0.39
CDK6 Q00534 1/20 0.39
PIK3CA P42336 1/20 0.38
MTOR P42345 1/20 0.38
OPRM1 P35372 1/20 0.38
OPRL1 P41146 1/20 0.38
LRRK2 Q5S007 3/20 0.37
PRKCH P24723 1/20 0.37
PRKCE Q02156 1/20 0.37
WNT3A P56704 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL26932372 0.99 HPGDS (0.44) HPGDSPRMT5PIM1PIM3PIM2
SCHEMBL26944604 0.86 HPGDS (0.45) HPGDSPRMT5PIM1PIM3PIM2
SCHEMBL31369865 0.83 HPGDS (0.44) HPGDSPRMT5PIM1PIM3PIM2
SCHEMBL12184922 0.81 GRIN2D (0.51) HPGDSPRMT5PIM1PIM3PIM2
Hydrochloric Acid SCHEMBL26922512 0.80 AOC3 (0.41) HPGDSPRMT5CCNT1CDK4CCND1
SCHEMBL26932376 0.80 HPGDS (0.48) HPGDSPRMT5PIM1PIM3PIM2
SCHEMBL9963945 0.78 GRIN2D (0.51) HPGDSPIM1PIM3PIM2ALOX5AP
SCHEMBL15205734 0.78 GRIN2D (0.51) HPGDSPRMT5PIM1PIM3PIM2
SCHEMBL19580579 0.78 RORC (0.47) PRMT5CCNT1CDK4CCND1CCND3
SCHEMBL30666373 0.76 KDM4E (0.44) HPGDSPIM1PIM3PIM2PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed