Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCND3 | P30281 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | LCAT | P04180 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662886 | 0.86 | HPGDS (0.45) | HPGDSPIK3CAMTORLRRK2CCNT1 | |
| Hydrochloric Acid SCHEMBL26932372 | 0.85 | HPGDS (0.44) | HPGDSPIK3CAMTORLRRK2CCNT1 | |
| SCHEMBL9963945 | 0.81 | GRIN2D (0.51) | HPGDSLRRK2CCNT1CDK4CCND1 | |
| SCHEMBL26932376 | 0.80 | HPGDS (0.48) | HPGDSCCNT1CDK4CCND1CCND3 | |
| SCHEMBL10201937 | 0.79 | PLD1 (0.49) | PIM1PIM3PIM2GPR119HRH3 | |
| SCHEMBL12184922 | 0.78 | GRIN2D (0.51) | HPGDSPIK3CAMTORLRRK2CCNT1 | |
| SCHEMBL15205734 | 0.78 | GRIN2D (0.51) | HPGDSLRRK2CCNT1CDK4CCND1 | |
| SCHEMBL31369865 | 0.78 | HPGDS (0.44) | HPGDSPRMT5PIM1PIM3PIM2 | |
| SCHEMBL14349679 | 0.78 | HPGDS (0.43) | HPGDSLRRK2CCNT1CDK4CCND1 | |
| SCHEMBL14349622 | 0.78 | HPGDS (0.45) | HPGDSLRRK2CCNT1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399307-A1 | ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE | AMYGDALA NEUROSCIENCES, INC. (US) | 2023-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399307-A1 | ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE | ALDH1A1, ALDH2, ALDH3A1 | HPGDS 2161/4885PIK3CA 3631/4885MTOR 3136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.