Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 5/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31370373 | 0.84 | HSD17B10 (0.46) | HSD17B10TYRSLC7A5PTGS1ALPI | |
| SCHEMBL34468285 | 0.84 | HSD17B10 (0.46) | HSD17B10TYRSLC7A5PTGS1ALPI | |
| SCHEMBL31662886 | 0.83 | HPGDS (0.45) | HPGDSPRMT5WNT3AAOC3ALOX5AP | |
| Hydrochloric Acid SCHEMBL26932372 | 0.82 | HPGDS (0.44) | HPGDSPRMT5WNT3AAOC3ALOX5AP | |
| SCHEMBL31688612 | 0.79 | AOC3 (0.54) | HSD17B10TYRSLC7A5PTGS1ALPI | |
| SCHEMBL26932376 | 0.79 | HPGDS (0.48) | HPGDSPRMT5KDM4EWNT3AAOC3 | |
| SCHEMBL26944604 | 0.78 | HPGDS (0.45) | HPGDSPRMT5WNT3AALOX5APPIM1 | |
| SCHEMBL31370121 | 0.77 | HSD17B10 (0.46) | HSD17B10SLC7A5PTGS1ALPIPKM | |
| SCHEMBL31370169 | 0.77 | AOC3 (0.56) | HSD17B10SLC7A5KDM4EALOX15AOC3 | |
| SCHEMBL31369460 | 0.76 | WNT3A (0.53) | HSD17B10TYRSLC7A5PTGS1ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | claimed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | HPGDS 2538/4885HSD17B10 3828/4885TYR 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.