Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | WNT1 | P04628 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.39 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665313 | 0.74 | SIGMAR1 (0.47) | KDM4EALDH1A1 | |
| SCHEMBL18710284 | 0.73 | L3MBTL1 (0.45) | WNT1GSK3BDYRK1AL3MBTL1TSHR | |
| SCHEMBL12471423 | 0.72 | IDO1 (0.43) | WNT1GSK3BDYRK1AKMT2AMEN1 | |
| SCHEMBL592839 | 0.72 | MEN1 (0.66) | ABL1RIN1KMT2AMEN1TSHR | |
| SCHEMBL26463387 | 0.72 | CACNA1H (0.43) | — | |
| SCHEMBL12471333 | 0.71 | ALDH1A1 (0.51) | ABL1KMT2AMEN1TSHRKDM4E | |
| SCHEMBL21476691 | 0.70 | ABL1 (0.47) | ABL1KMT2AMEN1TSHRKDM4E | |
| SCHEMBL16769735 | 0.69 | HRH3 (0.57) | KDM4EALDH1A1 | |
| SCHEMBL18034209 | 0.69 | THRA (0.46) | ABL1RIN1KMT2AMEN1KDM4E | |
| SCHEMBL28910476 | 0.69 | CXCR4 (0.61) | KMT2AMEN1KDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |