Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320699 | 0.85 | LMNA (0.42) | LMNAALDH1A1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL23748422 | 0.79 | LMNA (0.35) | LMNAALDH1A1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL31663089 | 0.79 | LMNA (0.35) | LMNAALDH1A1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL14691380 | 0.75 | VCAM1 (0.41) | ALDH1A1TSHRSMN1; SMN2MEN1MAPT | |
| SCHEMBL29471939 | 0.75 | S100B (0.43) | LMNAALDH1A1TSHR | |
| SCHEMBL15124607 | 0.75 | S100B (0.43) | LMNAALDH1A1TSHR | |
| SCHEMBL3237062 | 0.73 | TSHR (0.46) | ALDH1A1TSHRARDYRK1APDK2 | |
| SCHEMBL22914960 | 0.72 | TSHR (0.45) | LMNAALDH1A1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL27376196 | 0.72 | PTPN11 (0.33) | ALDH1A1CA1CA2 | |
| SCHEMBL23088100 | 0.71 | CYP2A6 (0.38) | LMNAALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |