Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.30 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320699 | 0.85 | LMNA (0.42) | LMNAALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL23748422 | 0.79 | LMNA (0.35) | LMNAALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL31663012 | 0.79 | LMNA (0.35) | LMNAALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL27547023 | 0.76 | AR (0.35) | EGLN2 | |
| SCHEMBL20079389 | 0.76 | LMNA (0.41) | LMNAALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL28948577 | 0.75 | REV1 (0.40) | — | |
| SCHEMBL1533157 | 0.73 | TSHR (0.46) | ALDH1A1TSHRNOTUMPDK2BCAT1 | |
| SCHEMBL22914956 | 0.72 | LMNA (0.37) | LMNAALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL14691418 | 0.72 | HTR3E (0.31) | — | |
| SCHEMBL28159009 | 0.72 | KDM1A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |