Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23412703 | 0.80 | ADORA3 (0.38) | ADORA3SCN9AGSK3BDYRK1ACYP17A1 | |
| SCHEMBL6183699 | 0.80 | CYP1A2 (0.41) | CYP1A2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL24343974 | 0.79 | CYP1A2 (0.62) | CYP1A2ALDH1A1KDM4ESMN1; SMN2TP53 | |
| SCHEMBL28458230 | 0.75 | ATR (0.40) | CYP1A2NPC1RAB9ASCN9AGSK3B | |
| SCHEMBL28997343 | 0.75 | SORT1 (0.48) | NPC1RAB9AKMT2A | |
| SCHEMBL19546004 | 0.75 | ALDH1A1 (0.67) | CYP1A2ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL21551425 | 0.74 | ATR (0.48) | ALDH1A1KDM4ESMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL30931841 | 0.74 | ATR (0.48) | ALDH1A1KDM4ESMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL6177797 | 0.74 | CYP17A1 (0.46) | GSK3BDYRK1ACYP17A1MAPTATR | |
| SCHEMBL29626657 | 0.74 | CYP17A1 (0.46) | GSK3BDYRK1ACYP17A1MAPTATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |