SCHEMBL31663371

SCHEMBL31663371

Cc1c[nH]c2c(CO[Si](C)(C)C(C)(C)C)ccc(Br)c12

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663308 0.84 BACE1 (0.32) BACE1
SCHEMBL31663167 0.81 BACE1 (0.33) BACE1
SCHEMBL31663376 0.76 REN (0.36) BACE1
SCHEMBL31663304 0.76 BACE1 (0.31) BACE1
SCHEMBL5391788 0.74 DUT (0.31)
SCHEMBL31663177 0.72 HTR2A (0.32)
SCHEMBL12002519 0.71 PYCR1 (0.39) BACE1
SCHEMBL20742459 0.71 BACE1 (0.33) BACE1
SCHEMBL25318008 0.70 ALOX5AP (0.33) BACE1
SCHEMBL17699894 0.69 CCNB2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149622-A1 WNK1 INHIBITORS DANIA THERAPEUTICS APS (DK) 2025-07-17 WO disclosed