SCHEMBL31663537

SCHEMBL31663537

Cc1cccc(-c2ccc(-c3ccccc3)c(-c3ccccc3)c2C#N)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.50
ALDH1A1 P00352 5/20 0.50
HPGD P15428 4/20 0.50
HSD17B10 Q99714 3/20 0.50
ADORA2A P29274 4/20 0.47
HTT P42858 3/20 0.47
ADRA2A P08913 1/20 0.47
ADORA1 P30542 3/20 0.46
TGFBR1 P36897 3/20 0.46
SQOR Q9Y6N5 1/20 0.43
NPSR1 Q6W5P4 2/20 0.43
PPARG P37231 1/20 0.43
NCOA2 Q15596 1/20 0.43
NCOA1 Q15788 1/20 0.43
NCOA3 Q9Y6Q9 1/20 0.43
MAPT P10636 2/20 0.42
LMNA P02545 2/20 0.42
GLA P06280 1/20 0.42
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663521 0.87 ADORA1 (0.53) KDM4EALDH1A1HPGDHSD17B10ADORA2A
SCHEMBL31663559 0.79 ALDH1A1 (0.60) KDM4EALDH1A1HPGDHSD17B10ADORA2A
SCHEMBL31663588 0.79 TGFBR1 (0.45) KDM4EALDH1A1HPGDHSD17B10TGFBR1
SCHEMBL31663624 0.78 ADORA2A (0.45) KDM4EALDH1A1HPGDHSD17B10ADORA2A
SCHEMBL31663529 0.75 TGFBR1 (0.46) KDM4EALDH1A1HPGDHSD17B10HTT
SCHEMBL12679765 0.72 ADORA1 (0.55) KDM4EALDH1A1HPGDHSD17B10ADORA2A
SCHEMBL31663594 0.72 ADORA1 (0.55) KDM4EALDH1A1HPGDHSD17B10ADORA2A
SCHEMBL31663596 0.72 ADORA1 (0.55) KDM4EALDH1A1HPGDHSD17B10ADORA2A
SCHEMBL9069187 0.72 ADORA2A (0.45) KDM4EALDH1A1HPGDHSD17B10ADORA2A
SCHEMBL18411290 0.70 TGFBR1 (0.54) TGFBR1GAAL3MBTL1CCR1CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250359476-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX INC (JP) 2025-11-20 US disclosed
US-12369492-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2025-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250359476-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, SLCO1B3, NDUFV3 KDM4E 4364/4885ALDH1A1 242/4885HPGD 2163/4885
US-12369492-B2 Composition of matter for use in organic light-emitting diodes CRY2, SLCO1B3, NDUFV3 KDM4E 4364/4885ALDH1A1 242/4885HPGD 2163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.