SCHEMBL31663633

SCHEMBL31663633

N#Cc1cc(-c2ccncc2)cc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 2/20 0.48
PIK3CD O00329 1/20 0.48
PIK3CB P42338 1/20 0.48
NOTUM Q6P988 1/20 0.47
SQOR Q9Y6N5 1/20 0.45
KDM4E B2RXH2 5/20 0.44
HPGD P15428 3/20 0.44
PDE3B Q13370 3/20 0.44
PDE3A Q14432 3/20 0.44
CYP2C19 P33261 2/20 0.44
PDE5A O76074 1/20 0.44
LMNA P02545 1/20 0.44
TSHR P16473 1/20 0.44
PTGS1 P23219 1/20 0.44
PDE4A P27815 1/20 0.44
BLM P54132 1/20 0.44
PDE4B Q07343 1/20 0.44
PDE4C Q08493 1/20 0.44
PDE4D Q08499 1/20 0.44
PRKACA P17612 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663569 0.85 CYP11B2 (0.47) KDM4EALDH1A1NPSR1TDP1GAA
SCHEMBL31663512 0.81 ADORA1 (0.49) SQORKDM4EHPGDCYP2C19LMNA
SCHEMBL16418476 0.81 NOTUM (0.58) PIK3CANOTUMKDM4ECYP2C19LMNA
SCHEMBL31663548 0.80 ALDH1A1 (0.49) SQORKDM4EHPGDCYP2C19LMNA
SCHEMBL31663532 0.79 NPSR1 (0.44) KDM4EHPGDCYP2C19LMNALRRK2
SCHEMBL31663508 0.79 GRIA1 (0.51) SQORKDM4ECYP2C19LMNAPDE4D
SCHEMBL31663575 0.78 ADORA1 (0.46) NOTUMSQORKDM4EHPGDPDE3B
SCHEMBL31663612 0.78 ADORA1 (0.46) NOTUMSQORKDM4EHPGDPDE3B
SCHEMBL31663547 0.77 KMT2A (0.48) SQORKDM4EHPGDCYP2C19LMNA
SCHEMBL31663627 0.77 CYP2C19 (0.49) PIK3CANOTUMSQORKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250359476-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX INC (JP) 2025-11-20 US disclosed
US-12369492-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2025-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250359476-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, SLCO1B3, NDUFV3 PIK3CA 2773/4885PIK3CD 3902/4885PIK3CB 3218/4885
US-12369492-B2 Composition of matter for use in organic light-emitting diodes CRY2, SLCO1B3, NDUFV3 PIK3CA 2773/4885PIK3CD 3902/4885PIK3CB 3218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.