SCHEMBL31664325

SCHEMBL31664325

COOc1ccccc1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.61
HPGD P15428 7/20 0.61
HSD17B10 Q99714 6/20 0.61
HTT P42858 2/20 0.61
ALDH1A1 P00352 9/20 0.60
HMGB1 P09429 2/20 0.60
NAPRT Q6XQN6 2/20 0.60
ESR1 P03372 1/20 0.60
ITGB3 P05106 1/20 0.60
ITGA2B P08514 1/20 0.60
TSHR P16473 1/20 0.60
GGT1 P19440 1/20 0.60
PTGS1 P23219 1/20 0.60
PTGS2 P35354 1/20 0.60
BLM P54132 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
USP2 O75604 1/20 0.53
PDE3A Q14432 1/20 0.53
MAPT P10636 1/20 0.53
LMNA P02545 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5459 1.00 KDM4E (0.61) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL23277174 0.98 KDM4E (0.59) KDM4EHPGDHSD17B10HTTALDH1A1
Fluoride SCHEMBL28851572 0.98 KDM4E (0.59) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL29010714 0.87 KDM4E (0.63) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL13369192 0.85 KDM4E (0.50) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL29365231 0.83 HTT (0.78) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL3527 0.83 HTT (0.78) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL15106396 0.82 KDM4E (0.46) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL7672827 0.82 IRAK4 (0.59) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL28178564 0.82 SLC6A3 (0.61) KDM4EHSD17B10HTTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4587028-A2 COMPOUNDS AND METHODS FOR IMPROVING HEALTH Acurx Pharmaceuticals, Inc. (US) 2025-07-23 EP disclosed