Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31666982 | 0.89 | HPGD (0.43) | MAPK1ALDH1A1IL4I1MEN1KMT2A | |
| SCHEMBL31667167 | 0.87 | MAPK1 (0.39) | MAPK1ALDH1A1IL4I1MEN1KMT2A | |
| SCHEMBL32687030 | 0.87 | ALDH1A1 (0.44) | MAPK1ALDH1A1IL4I1MEN1KMT2A | |
| SCHEMBL32686751 | 0.86 | PDE3B (0.42) | MAPK1ALDH1A1IL4I1MEN1KMT2A | |
| SCHEMBL31667119 | 0.83 | IL4I1 (0.37) | MAPK1ALDH1A1IL4I1MEN1KMT2A | |
| SCHEMBL31667363 | 0.83 | IL4I1 (0.41) | MAPK1IL4I1MEN1KMT2APDE10A | |
| SCHEMBL31667717 | 0.82 | MEN1 (0.45) | MAPK1IL4I1MEN1KMT2AHPGD | |
| SCHEMBL31667679 | 0.82 | MEN1 (0.45) | MAPK1IL4I1MEN1KMT2AHPGD | |
| SCHEMBL31666930 | 0.82 | MEN1 (0.45) | MAPK1IL4I1MEN1KMT2AHPGD | |
| SCHEMBL31667602 | 0.82 | IL4I1 (0.42) | MAPK1ALDH1A1IL4I1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | SIRONAX LTD (KY) | 2026-03-19 | — | — | US | disclosed |
| EP-4590674-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd (KY) | 2025-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | NAMPT, NNMT, SARM1 | MAPK1 1908/4885ALDH1A1 2719/4885IL4I1 2872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.